Hans Frederik Blichfeldt, 1873-1945

Dmd058347 1873..1880

Historically, since the metabolism of administered peptide/protein drugs (“biotherapeutics”) has been expected to undergo predictable pathways similar to endogenous proteins, comprehensive biotherapeutic metabolism studies have not been widely reported in the literature. However, since biotherapeutics have rapidly evolved into an impressive array of eclectic modalities, there has been a shift t...

Blichfeldt-type Inequalities and Central Symmetry

A classical result of Blichfeldt, from 1921, gives a sharp lower bound on the volume of a convex body K, whose lattice points span the whole space, in terms of the lattice point enumerator #(K∩Z). We are interested in a version of this inequality on the set of 0-symmetric convex bodies. Our motivation to study this problem comes from a lack of methods that exploit the symmetry assumption in pro...

Alexis Carrel (1873-1944)

Alexis Carrel [5] was a doctor and researcher who studied tissue cultures. He continued Ross Granville Harrison?s research and produced many improvements in the field of tissue culture and surgery. He was the recipient of the 1912 Nobel Prize in Physiology or Medicine [6] for his development of surgical techniques to repair blood vessels. Carrel was born on 28 June 1873 in Sainte-Foy-les-Lyon, ...

C2lc21146g 1865..1873

Mechanotransduction is known as the cellular mechanism converting insoluble biophysical signals in the local cellular microenvironment (e.g. matrix rigidity, external mechanical forces, and fluid shear) into intracellular signalling to regulate cellular behaviours. While microfluidic technologies support a precise and independent control of soluble factors in the cellular microenvironment (e.g....

Joseph Saxton . 1799 - 1873